Gastric cancer


Gastric cancer is one of the most common types of cancer. There are considerable geographical differences in incidence, with the highest in North-Eastern Asia. In the Netherlands the incidence is 7,3 per 100.000 people. 60% are male and it mostly occur above 70 years of age.

-Gastroscopy with biopsies
-CT thoracic and abdominal
-Diagnostic laparoscopy in patients with possible operable tumour that have a radiology classification of T3-T4

Early gastric cancer

Preoperative treatment:

-Neoajuvant chemotherapy: fluorouracil, leucovorin, oxaliplatin, docetaxel
-When treated prior: epirubicin, cisplatin and 5-fluorouracil (5-FU)
Adjuvante behandeling: Chemotherapy
Metastasized: Chemotherapy +/- Trastuzumab (HER2 positive)


Shim CN, Lee SK. Endoscopic submucosal dissection for undifferentiated-type early gastric cancer: Do we have enough data to support this? World J Gastroenterol 2014; 20(14): 3938-3949

Smyth et al. Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals ofOncology 27(Supplement5): v38–v49,2016. doi:10.1093/annonc/mdw350