Effects of Withdrawal of Immunomodulators or Biologic Agents IBD

Withdrawal of IBD (Inflammatory Bowel Disease) therapy; for example anti-TNF. 50% or more of patients with IBD who cease/stop therapy have a disease relapse. The decision to withdraw a drug should be made for each individual based on patient preference, disease markers, consequences of relapse, safety, and cost.

References:

Torres, J., Boyapati, R. K., Kennedy, N. A., Louis, E., Colombel, J.-F., & Satsangi, J. (2015). Systematic Review of Effects of Withdrawal of Immunomodulators or Biologic Agents From Patients With Inflammatory Bowel Disease. Gastroenterology, 149(7), 1716–1730. doi:10.1053/j.gastro.2015.08.055