Stage 1 (T1-2 N0M0):
Wide surgical resection and anastomosis. No adjuvant chemotherapy.

Stage II A, B, C (T3 N0 M0, T4 a-b N0 M0)
-Wide surgical resection and anastomosis.
-Following surgery, adjuvant therapy should not be routinely recommended for unselected patients.

Stage III (any T, N1-N2, M0)
-Wide surgical resection and anastomosis. -Following surgery, adjuvant chemotherapy

Metastic disease