Lynch syndrome (HNPCC) surveillance: European Society of Gastrointestinal Endoscopy (ESGE) recommendations

-ESGE recommends starting colonoscopy surveillance at
the age of 25 years for MLH1 and MSH2 mutation carriers
and at the age of 35 years for MSH6 and PMS2 mutation
carriers.

-ESGE recommends a high quality surveillance colonoscopy
every 2 years in asymptomatic individuals with Lynch
syndrome.

-ESGE does not recommend routine gastric surveillance in
individuals with Lynch syndrome.

-ESGE suggests (non-invasive) testing for Helicobacter
pylori in individuals with Lynch syndrome.

-Transvaginal ultrasound every 2 years from 40-60 years

Related articles:
–Fap vs Lynch
–Polyposis syndromes

References:

Endoscopic management of Lynch syndrome and of familial risk of colorectal cancer: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

Giardiello, Francis M MD¹; Allen, John I²; Axilbund, Jennifer E¹; Boland, Richard C³; Burke, Carol A⁴; Burt, Randall W⁵; Church, James M⁴; Dominitz, Jason A^{6, 7}; Johnson, David A⁸; Kaltenbach, Tonya⁹; Levin, Theodore R¹⁰; Lieberman, David A¹¹; Robertson, Douglas J^{12, 13}; Syngal, Sapna^{14, 15, 16}; Rex, Douglas K¹⁷ Guidelines on Genetic Evaluation and Management of Lynch Syndrome: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer, American Journal of Gastroenterology: August 2014 – Volume 109 – Issue 8 – p 1159-1179 doi: 10.1038/ajg.2014.186