Category : Hepatology

Hepatocellular carcinoma (HCC) treatment strategy in cirrhotic liver. EASL guidelines. Related articles:Liver transplantation criteria for HCCBenign liver tumoursLiver cirrhosis follow-up References: EASL guideline HCC Forner A, et al. Lancet 2018;391:1301–1314 EASL CPG HCC. J Hepatol 2018; doi: 10.1016/j.jhep.2..

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Extended criteria (liver) donor (ECD) Related articles:Liver transplantation criteria for HCCKing’s College criteria for liver transplantationRisk of liver decompensation after hepatectomy Definition of ECD donorsThe ECD graft represents an organ with unfavourable characteristicsassociated with suboptimal post-transplant outcomes thatfall into two main risk categories: poor graft function and potentialfor disease transmission. Within the poor graft function ..

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Liver transplantation criteria Hepatocellular Carcinoma (HCC) – Milan criteria Related articles:HCC treatmentRisk of liver decompensation after hepatectomyKing’s College criteria for liver transplantationExtended criteria donor (ECD) Milan criteria Solitary HCC <5 cm diameter OR ≤3 nodules with diameter <3 cm UCSF criteria1 Single lesion ≤6.5 cm in diameter OR 2–3 lesions ≤4.5 cm; total tumour diameter ..

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Alcoholic hepatitis Treatment algorithm in patients with suspected alcoholic hepatitis. Calculate Maddrey and Lille score for indication and evaluation of steroid treatment Related articles/links:Maddrey scoreLille scoreAcute liver failureWilson diseaseAutoimmune hepatitis (AIH) likelihood scoreAutoimmune hepatitis (AIH) References: EASL Clinical Practice Guidelines: Management of alcohol-relatedliv..

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Gallbladder polyp Related articles:Bile duct cysts: Todani classification A gallbladder polyp is a common incidental finding on ultrasound. Most suspected gallbladder polyps on ultrasound do not have malignant potential and are either hyperplastic or lipid deposits (cholesterolosis), but some of the gallbladder polyps are (pre)malignant. Therefore follow-up or cholecystectomy is advised. A gallbladder polyp is ..

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Benign liver tumours Related articles:HCC treatmentRisk of liver decompensation after hepatectomy Haemangioma FNH HCA Estimated prevalence Common ~5%* Less common 0.03% Rare ≤0.004% Age 30–50 years 20–40 years All ages Gender F > M F ~ M F >> M US Hyperechoic Varied Varied CT Centripetal enhancement Central scar Varied MRI Centripetal enhancement Hyperintense T2-w ..

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Ascites characterisation Related articles:Refractory ascitesLiver cirrhosis follow-upHepatorenal syndrome (HRS)Hepatopulmonary syndrome (HPS)Hepatic Encephalopathy gradeKing’s College criteria for liver transplantation Overview of ascites characterisation by calculating the SAAG (Serum-Ascites Albumin Gradient). Grading of ascites. Contraindications to paracentesis. 20 gr of Albumine for every 2 L ascites drainage above 5 L References: Management of Decompensated Cirrhosis EASL..

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Refractory ascites: definition and diagnostic criteria for refractory ascites in cirrhosis. Related articles:Ascites characterisationHepatic Encephalopathy gradeHepatorenal syndrome (HRS)Hepatopulmonary syndrome (HPS)Liver cirrhosis follow-upNon cirrhotic portal hypertension (NCPH)Varices surveillance References: EASL Clinical Practice Guidelines for the management of patients with decompensated..

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Acute kidney Injury (AKI) and hepatorenal syndrome (HRS) in patients with liver cirrhosis; diagnostic criteria, classification and management. Hepato-renal classification: HRS type 1: characterized by a rapid and progressive impairment in renal function (increase in serum creatinine of equal to or greater than 100% compared to baseline to a level higher than 2.5 mg/dl in ..

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The Child-Pugh score was originally developed in 1973 to predict mortality during surgery, but is often used to determine prognosis in patients with liver cirrhosis. It is also known as the Child-Turcotte-Pugh score. Calculator Related articles: Acute liver failure Hepatic encephalopathy score King‘s college criteria for liver transplantation. Liver cirrhosis..

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