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Cancer risk in primary sclerosing cholangitis Hepatocellular carcinoma: 0.3%-2.8% lifetime incidence Gallbladder carcinoma: 1%-3.5% lifetime incidence (10x general population) Cholangiocarcinoma: up to 20% lifetime incidence (400x-1500x general population) Colorectal cancer: 20-30% lifetime incidence in PSC-IBD (10x risk general population, 4x risk over UC) References: Fung BM, Lindor KD, Tabibian JH. Cancer risk in primary sclerosing ..

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Tokyo Guidelines 2018: initial management of acute biliary infection and flowchart for acute cholangitis Severity assessment criteria for acute cholangitis Grade III (severe) acute cholangitisOnset of dysfunction at least in any one of thefollowing organs/systems:-Cardiovascular dysfunction: hypotension requiring dopamine ≥5 lg/kg per min, or any dose of norepinephrine-Neurological dysfunction: disturbance of consciousness-Respiratory dysfunction: PaO2/FiO2 ratio ..

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BAVENO VI guideline for portal hypertension selection of statements Identification of patients with cACLD who can safely avoid screeningendoscopy (new)-Patients with a liver stiffness <20 kPa and with a platelet count >150,000 have a very low risk of having varices requiring treatment, and can avoid screening endoscopy-These patients can be followed up by yearly repetition ..

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Harvey-Bradshaw index for Clinical disease activity in Crohn’s Disease Parameter Input and score 1. Patient well-being(previous day) 0 = very well1 = slightly below par2 = poor3 = very poor4 = terrible 2. Abdominal pain(previous day) 0 = none 1 = mild2 = moderate3 = severe 3. Number of liquid or soft stools(previous day) blank ..

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Truelove and Witts severity index for Ulcerative Colitis – Mild Moderate Severe Bowel movements (number per day) Fewer than 4 4–6 6 or more plus at least 1 of the features of systemic upset (marked with * below) Blood in stools No more than small amounts of blood Between mild and severe Visible blood Fever ..

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Esophageal lichen planus References: Franziska Schauer, Carmen Monasterio, Kristin Technau-Hafsi, JohannesSteffen Kern, Adhara Lazaro, Peter Deibert, Peter Hasselblatt, Henning Schwacha, Steffen Heeg, Volker Brass, Armin Küllmer, Arthur Robert Schmidt, Annette Schmitt-Graeff & Wolfgang Kreisel. (2019) Esophageal lichen planus: towards diagnosis of an underdiagnosed disease, Scandinavian Journal of Gastroenterology, 54:10, 1189-1198, DOI: 10.1080/00365521.20..

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Colonoscopy adverse events rates vary a greatly between studies, especially the bleeding rates Adverse events rates in all diagnostic colonoscopies:Bleeding: 1 in 100-1000 (0.1-1%)Perforation: 1 in 1000-2000 (0.05-0.1%) Adverse events rates in diagnostic colonoscopy with polypectomy:Bleeding: 1 in 15-100 (1%-6.5%)Perforation: 1 in 500 (0.2%) These statistics are based on polypectomy with a maximum polyp size ..

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