Therapeutical options in the management of pruritus associated with jaundice (cholestatic liver disease). Cholestyramine; rifampicin; naltrexone; sertraline; References: EASL Clinical Practice Guidelines: Management of cholestatic liver diseases. (2009) Up to date Jaundice associated pruritis: A review of pathophysiology and treatment. World J Gastro. 2015 Tajiri K, Shimizu Y. Recent advances in the management of pruritus in ..